Biodiscovery | UniSC | University of the Sunshine Coast, Queensland, Australia

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Biodiscovery

Jellyfish
Spider From Volker Herzigr
Ctenophore

Biodiscovery Research

This theme focuses on the discovery of bioactive natural products and proteins from natural sources for applications mainly in the medical space but also as cutting edge technologies for aquaculture and to explore and understand the biology of life. The research conducted within this theme relies on state-of-the-art spectroscopy and spectrometry capabilities within the Advanced Instrument Facility at the Sippy Downs campus, such as triple quadrupole LC MS/MS, quadrupole Time-of-Flight MS/MS and NMR. The major areas of focus are discovery and characterisation of novel compounds with therapeutic potential (targeting bacteria, cancer, pain, epilepsy, gastrointestinal disorders and wounds) sourced primarily from plants, actinomycetes, fungi, arthropod venoms, aquatic species and bee products.

This theme currently includes significant research programs focusing on:

Research Funding

Our research is funded both through strong industry partnerships as well as through competitive grants involving diverse collaborations from across the globe.

Key researchers and research areas

Tianfang Wang
Dr Tianfang Wang
  • Functional proteomics
  • Peptide chemistry
  • Biodiscovery
  • Natural bioactive peptides
  • Computational chemistry
David McMillan
Associate Professor David McMillan
  • Biodiscovery
  • Drug development
  • Natural products chemistry
  • Population genetics
  • Conservation genetics
  • Plant reproductive biology
Fraser Russell
Associate Professor Fraser Russell
  • Investigation of anti-inflammatory and anti-oxidant activity of Australian honeys. This project is supported by a Cooperative Research Centres (CRC) grant.
  • Determination of the efficacy of omega-3 fatty acids in modulating immune responses in blood-derived macrophages from patients with abdominal aortic aneurysm.
  • Examination of the wound-healing potential of Australian stingless bee cerumen. This project entails isolation of novel compounds from cerumen and examination of their capacity to modify signalling events that are central to chronic non-healing wounds.
Volker Herzig
Associate Professor Volker Herzig
  • Arthropod venoms
  • Peptide toxins
  • Ion channels
  • Pharmacology
  • Toxinology
  • Molecular biology
  • Parasitology
  • Bioinsecticides
Scott Cummins
Professor Scott Cummins
  • Molecular neuroethology
  • Protein pheromones
  • Neuropeptides
  • Functional genomics
  • Invertebrate biology
  • Invasive species